Reponse Pharmacogenomic Testing

Pharmacogenomics provides information on a patient's genetic make-up that can be used to determine how a prescribed drug will relate with him or her. This will give the physician valuable insight into the efficacy of the drug but also potential undesired drug reactions.

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Our DNA acts as a template to produce very important proteins known as enzymes. These enzymes are used to act upon certain target substances, like a drug, in order to trigger a reaction.

In this case, the reaction would ideally be what allows the drug to do its intended work. A pharmacogenomics test will provide the information needed to allow the physician to prescribe the right medications and avoid those that would be both inefficient and/or could cause adverse drug interactions.

By isolating and examining the regions of a patient's DNA that code for the enzymes of interest, we can provide the following answers:

 

By isolating and examining the regions of a patient's DNA that code for the enzymes of interest, we can provide the following answers:

Q: How do enzymes interact with their targets, and how does the patient's genetic makeup affect these interactions?
A: Enzymes modify drugs into their active and inactive metabolites. A person's genetic makeup may seriously affect how well certain enzymes perform.


Q: How well does the patient metabolize/utilize drugs, and what personal factors are being used to aid in drug selection?
A: RESPONSE acts as a lifelong prescribing roadmap, steering the provider towards drugs that are metabolized efficiently and away from those that are not.


Q: Is there a system to identify when a patient is taking a medication that is poorly suited for them?
A: RESPONSE acts as a safeguard, protecting both physician and patient from undesirable adverse drug reactions.


Q: How can a physician reduce drug-drug interactions when a patient is prescribed multiple medications?
A: RESPONSE flags potentially dangerous interactions between drugs and often suggests suitable alternatives.

RESPONSE OFFERS

- A lifelong prescribing roadmap that will steer the provider toward drugs that are metabolized efficiently and away from those that are not.
- A safeguard, protecting both physician and patient from undesirable, adverse drug reactions and potentially dangerous drug-drug interactions.
- In cases of potential adverse drug reactions or unfavorable drug-drug interactions, RESPONSE™ often suggests suitable alternatives.

Who To Test?

- Patients that experience less than optimal results from prescribed medications.
- Patients with a personal or family history of adverse drug reactions in response to certain medications.
- Patients taking multiple prescribed medications for multiple chronic conditions.

FDA studies estimate that 7% of hospitalized patients have a serious adverse drug reaction with a fatality rate of 0.32%.

There are more than 2,216,000 serious ADRs in hospitalized patients, causing over 106,000 deaths annually.